Alkaloid is determined by the acidity of molecular sources (precursors), base on the metabolic pathway that use to form that molecule. If the biosynthesis of the alkaloid unknown, alkaloid then classified into the name of their compound, include of compound that not contain of nitrogen, as an example, alkaloid of opium, sometimes called as phenanthrenes, or base according to the name of plant or animals where that substance is isolated. After analyses, grouping of alkaloid change according to the result of analyses, usually contain amine name.
- Piridine group: piperine, coniine, trigonelline, arecoline, arecaidine, guvacine, cytisine, lobeline, nikotine, anabasine, sparteine, pelletierine
- Pyrrolidine Group: hygrine, cuscohygrine, nikotina
- Tropane group: atropine, kokaine, ecgonine, scopolamine, catuabine

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